Sharapova moved into the fourth round at Flushing Meadows with a 6-2 6-4 win over Sabine Lisicki on Friday and will come up against the Dane for the first time since Indian Wells a year ago.
The Russian fifth seed holds a 5-2 career advantage over the world number 11 but Wozniacki has been in strong form this year - winning the Istanbul Open while making the semi-finals in Dubai, Monterrey. Eastbourne and Cincinnati.
And ahead of the meeting between the former world number ones, Sharapova feels both players will know one another's games very well.
"She's having a really good summer so far. She's really raising her level to where she wants it to be," said Sharapova.
"Although we haven't played in a while, we have played against each other many times and there are no secrets on our games. We've been on the tour for many years.
"So I expect a tough match, a physical match. She always gets a lot of balls back. So it's going to be a tough match."
On her victory over Germany's world number 28 Lisicki, Sharapova revealed her pleasure at seeing off a potentially troublesome opponent and, furthermore, doing so in just an hour and 41 minutes.
"[Lisicki] is a very dangerous and a tricky opponent," the Russian continued.
"She's very capable of playing well at the slams, of raising her level against the top players. And that was something I was very well aware of and I felt I stepped up to the challenge.
"I'm happy I finished the match at two sets. I had a very tough, physical, two-and-a-half-hour match a couple of days ago so I was glad I was able to finish this one a bit quicker and give myself a little bit more time to recover for the next one."