AEL claimed a shock 2-1 victory over Belgian giants Anderlecht in an intriguing Champions League play-off in Nicosia.
The Cypriot side, attempting to emulate APOEL Nicosia's feats last season, took a deserved advantage thanks to Rui Miguel's late winner.
Dosa Junior headed AEL into a 34th-minute lead in the first leg encounter at the GSP Stadium before Dieudonne Mbokani fired home in the 62nd minute to equalise for Anderlecht.
Ten minutes later Edmar negotiated his way past the back four, laying off to Rui Miguel, whose angled shot hit the post and slowly creeped past the goalkeeper, despite getting a hand to it.
Anderlecht's hopes of an equaliser were soon dented when Milan Jovanovic was sent off for a second yellow.
Anderlecht, who suffered their first defeat in six matches, will hope to rectify the problem in the return leg in Belgium next Wednesday.
Braga were held to a 1-1 draw by Serie A side Udinese at the AXA Stadium in an entertaining first leg.
Antonio Di Natale's pin-point free-kick met the head of Dusan Basta, who powerfully headed past Beto to hand the Italian side a valuable away goal in the 23rd minute.
But the hosts equalised in the 68th, with Ismaily's effort from 30 yards rattling in off the crossbar.
BATE Borisov claimed a comfortable 2-0 win over Israeli side Ironi Kiryat Shmona at the Dinamo Stadium in Minsk to assume the first-leg ascendancy.
The Israeli side, attempting to qualify for their first Champions League, fell to a double to Vitali Rodionov, who scored in both halves, and had Dusan Matovic sent off in the 71st minute.
Malaga moved closer to qualification with an impressive 2-0 victory over Greek side Panathinaikos in Spain.
The hosts dominated from the off, and took the lead on 17 minutes through Argentine Martin Demichelis, who provided the decisive touch to Joaquin's free-kick.
In the 34th minute the Greek side were again punished by a slick one-two from Enzo Maresca and Isco before picking out Eliseu to crisply volley home the second.
Dinamo Zagreb won 2-1 against Maribor at the Stadion Maksimir despite an own goal from Milan Badelj.
Defender Duje Cop netted after 10 minutes before Badelj atoned for his mishap with the winner in the 74th minute.