Valencia, Braga, Wolfsburg, Aston Villa, Hamburg and Ajax booked their places in the knockout stages of the UEFA Cup after a pulsating evening of European football that delivered 26 goals across eight games.
Valencia got the point it needed to progress through to the next round from Group G thanks to Nikola Zigic's second-half equaliser against Club Brugge in a 1-1 draw at the Mestalla.
Both goals came from headers, with Zigic's 60th-minute effort cancelling out Antonin Alcaraz's first-half opener for Club Brugge.
Villa advanced to the last 32 despite crashing to a 2-1 defeat against 10-man MSK Zilina.
Goals from Vladimir Leitner, who was sent off in the second half for two bookable offences, and Peter Styvar put MSK in control before Nathan Delfouneso pulled one back on his full debut for Martin O'Neill's side.
Villa could not find an equaliser but still joins Hamburg and Ajax - who did not play this week - in qualifying from Group F.
Hamburg went through courtesy of goals from Croatian duo Ivica Olic and Mladen Petric in a 2-0 win over Slavia Prague, which is now out.
Olic pounced to score on the half-hour mark and Petric netted an injury-time penalty - after Slavia keeper Martin Vaniak had been sent off for bringing down David Jarolim in the area.
Braga confirmed its passage with a 2-1 win over Heerenveen in Holland.
Gerald Sibon had put the hosts ahead in the first half from a free-kick, but the Portuguese side hit back through Wason Renteria and a Luis Aguiar free-kick.
With Wolfsburg avoiding defeat at home to Portsmouth, a win for Braga was enough to secure its passage.
David James' howler sent Portsmouth crashing out as it lost 3-2 against the Wolves.
Edin Dzeko fired the hosts into an early lead before Pompey hit back through Jermain Defoe and Arnold Mvuemba, although Christian Gentner levelled things up before the break.
James then gifted the Germans a third in the 74th minute when Zvjezdan Misimovic took the ball from his feet and rolled it into the net - although the England man partially atoned with a penalty save from the same player five minutes later.
A Vagner Love hat-trick secured CSKA's position at the top of UEFA Cup Group H and put a dent in Nancy's qualification hopes after a seven-goal thriller at the Marcel Picot stadium.
The Brazilian scored two minutes from the end to seal the win after Nancy thought it had stolen a point through Basile Camerling's late strike. Vagner Love and fellow Brazilian Ramon had given the visitors a 3-1 lead over Nancy, for whom Monsef Zerka and Julien Feret also tallied.
Deportivo La Coruna must wait until its final Group H match to secure its passage to the last 32 after a 1-1 draw with Lech Poznan in Poland.
Diego Colotto put the visitors ahead in the first minute but Hernan Rengifo levelled before half-time for Lech and Deportivo were grateful to keeper Daniel Aranzubia for some fine saves.
A late goal from Mikael Antonsson ensured FC Copenhagen kept alive its hopes with a 1-1 draw against Scandinavian rivals Rosenborg in Group G.
Steffen Iversen's first-half strike looked to have earned the Norwegians the points but Antonsson's header with five minutes remaining sparked celebrations at Parken.
The result means FCK's final group match against Club Brugge will be decisive as both teams look to finish in the top three.