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The champion leg-spinner was forced to withdraw early in the match at Lord's when Lee's first delivery struck him hard in the glove.
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Lords' twitter account posted a picture of Warne's hand appearing to be red, swollen and badly damaged a short time later.
Here's @ShaneWarne's suspected broken hand after that incident with @BrettLee_58 #mccvrow pic.twitter.com/3wEDV19PyV
— Lord's Ground (@HomeOfCricket) July 5, 2014
Warne tweeted his disappointment a short time later with confirmation that the hand was fractured.
Sad news, X ray shows a broken hand !!! Very disappointing not to be out there playing. Thankyou for all your kind messages....
— Shane Warne (@ShaneWarne) July 5, 2014
Much of the crowd was looking forward to seeing Warne, the captain of the Rest of the World XI, bowl his leg spinners at MCC skipper Sachin Tendulkar.
Warne's injury meant the famous Lords media centre got to spend time with the leg-spinning wizard....
.@shanewarne has made his way up to the Media Centre... #mccvrow pic.twitter.com/NfkLtzbCoN
— Lord's Ground (@HomeOfCricket) July 5, 2014
Aussie Aaron Finch starred with 181 not out to guide the MCC to victory as they successfully chased down the Rest of the World's 293 - that was set up by Yuvraj Singh's 132.